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What is Stage 4 Endometrial Cancer?


There is a good chance that cancer has spread to other body areas. Stage IV cancer is separated into two categories: IVA and IVB, which are determined by how far the disease has spread.

Cancer has progressed to the bladder or intestinal wall at the time of diagnosis in stage IVA. Cancer has progressed to other body regions other than the pelvis at stage IVB, such as the belly or lymph nodes in the groin.

What does stage 4 endometrial cancer mean?

A few of the lymph nodes in the lower groin have been infected with cancerous cells, which have moved to the bladder or lower section of the large intestine. There are two types of uterine cancer at stage 4:

The malignancy has progressed to the rectum or bladder’s inner lining called the mucosa. Although it may have expanded to neighboring lymph nodes, it has not migrated to other locations.

Cancer has progressed to distal lymph nodes, abdomen, the omentum, or other organs that are not directly related to the uterine, such as omentum, bones, or lungs in Stage 4B. The malignancy might be of any size as far as lymph nodes are concerned.

Stage 4 endometrial cancer symptoms

Like stage III, they’re the same. If cancer has progressed to other parts of your body, you may also experience symptoms such as aches in the bone or breathlessness.

Stage 4 endometrial cancer survivors

Your doctor may discuss your treatment outcomes regarding the percentage of patients who have survived. A frequent benchmark is five years. The proportion of women diagnosed with endometrial cancer who survive for at least five years is shown.

Only previous figures are included in this estimation, and it doesn’t consider the improvements in care and prognosis that are constantly occurring.

Uterine cancer patients had an 82percent five-year chance of survival. Seventy-nine percent of those who live to the age of 10 will still be alive.

Treatment for endometrial cancer stage 4

There are few situations where surgery can eliminate all of stage IV endometrial cancer because the disease has progressed too far. There is still a chance that a hysterectomy and fallopian tubes, and ovary removal will be necessary to avoid heavy bleeding.

Even radiation may be employed in this case. It’s possible to utilize hormone treatment if cancer has progressed to other places of the body.

If you have a high-grade tumor or a tumor that doesn’t have progesterone or estrogen receptors, hormone treatment isn’t likely to help.

  • Some women may benefit from the use of chemo medicines in combination. Doxorubicin, Paclitaxel, and either carboplatin or cisplatin are the most often utilized medicines. These medicines are frequently used jointly. Chemotherapy for Stage IV carcinosarcoma is frequently the same as for Stage III. Combining cisplatin with ifosfamide or Paclitaxel is another option.
  • Some females with severe endometrial cancer may potentially benefit from targeted medications and immunotherapy treatments.
  • Consider participating in research studies of chemotherapy or even other novel therapies for women with advanced endometrial cancer (stage IV).

Stage 4 endometrial cancer survival rates

Stage 4 ovarian cancer has a five-year survival rate of roughly 17%. Survival rates are frequently based on large-scale research, although they cannot predict individual outcomes. In addition to the woman’s overall health, cancer’s grade and response to therapy affect her outlook.

On average, 3 out of 4 ovarian cancer patients survive at least a year following diagnosis. Nearly half that is 46% of ovarian cancer patients, survive at least five years following diagnosis. Women diagnosed before age 65 fare better than older females.

Stage 4 endometrial cancer life expectancy

A prediction of the course and fate of cancer is given in a prognosis report. It is sometimes expressed as a proportion of the population predicted to live for more than five or ten years.

According to statistics, endometrial cancer has a 5-year survival rate of around 81 percent on average. The stage of the disease determines individual survival rates at the time of diagnosis, as well as other factors.

When uterine cancer is discovered in its initial stage IA [1A], it has the highest chance of being cured. Survival rates may reach as high as 90 percent in certain instances.

As the stage of cancer progresses, the likelihood of survival decreases. Women who are diagnosed with stage IV (4) endometrial cancer have a five-year survival rate of around 15 percent.


Moreover, Early-stage endometrial cancer is the most common kind of cancer detected in women, accounting for about a 70percent of all cases.

Another 20percent of the total are diagnosed after cancer has progressed to surrounding lymph nodes and organs, and around 10percent are identified when it has migrated to distant areas of the body.


    About Author

    Dr. Nilesh is a renowned Cancer surgeon/consultant practicing at SSO Hospital, Infinity Media Surge Hospital, and Navkaar Cancer Clinic Mumbai and he is also a visiting consultant at various hospitals in Mumbai, Thane, Dombivali, Kalyan, Navi Mumbai, etc. With over 10+ years of experience, he is highly trained and specialized in performing GI & Gynae cancer surgery procedures from the simplest to the most complicated surgeries.

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